Natura Bissé was a pioneer in applying non-destructive acid hydrolysis of proteins (HVA system) to the world of cosmetics. This system gives access to the basic component elements of protein, amino acids, not only in their free form, but also with all of their properties intact.

The incorporation of natural amino acids in their free form of the most important proteins to skin, Collagen, Elastin and Keratin, was a major milestone in cosmetics; individual (free form) amino acids truly penetrate skin, where they can be effective because their properties remain unaltered, thanks to the HVA system.


NATURA BISSÉ launched its first five products based on natural free form amino acid technology. Those first creams included ESSENTIAL SHOCK CREAM C+E (with natural free form collagen and elastin amino acids) that have considerable power to refirm skin.
The resounding success of this exceptional product gave rise to the creation of a full treatment line that included, in addition, antioxidant vitamins and isoflavones (plant-based phytoestrogens) capable of compensating for hormone deficiencies and refirming even the most demanding mature skin.

  • The essence of skin regeneration

    Tanks to its advanced research, NATURA BISSÉ has updated and redesigned this line. The ESSENTIAL SHOCK INTENSE LINE is a new generation of cosmetics that acts as an anti-aging, intensive shock treatment for mature skin, promoting multiple-level skin restoration based on:

  • Proteoglycan-Derma complex

    A powerful synergy between Proteoglycans and Glycosaminoglycans, hydrolyzed for proper assimilation, combined with a highly specific Lipopeptide to restore and refirm skin. Proteoglycans are key elements to skin gaining greater volume, hydration, density and elasticity.

  • Amino essence cocktail

    A very complete cocktail of Natural Free Form Collagen and Elastin Amino Acids, plus an extra dose of "Essential" Amino Acids (L-Alanine, L-Threonine, L-Isoleucine, L-Histidine, L-Fenilalanin), and "Non-essential" Amino Acids (L-Arginine, L-Aspartic acid, Glycine, L-Serin, L-Valine, L-Prolin), all of which are vital to synthesizing new protein fibers. This complex nourishment successfully regenerates skin and provides the tolerance and firmness inherent to youthful skin.